The two reported multigenerational pedigrees show a pattern consistent with autosomal dominant inheritance. No causative mutation has been identified but mapping suggests a locus at 1q31-q32.2 that segregates with the condition.
Nystagmus 2 (164100), nystagmus 3 (608345), and nystagmus 4 (614826) are other autosomal dominant forms of simple nystagmus but they are unique disorders as they map to other chromosomal locations.
Several forms of X-linked recessive inheritance are contained in this database: NYS1, NYS5, and NYS6.
