Most dislocated lenses of non-traumatic origin are associated with syndromes, particularly those with defective connective tissue. However, a few families with dislocated lenses have been reported in which no evidence of defective collagen is present. The lens is most commonly displaced temporally, often creating myopic astigmatism. The mean age of discovery of the dislocated lenses is about 2 years of age. The eye is otherwise normally formed, intraocular pressure is normal, and the axial length is in the normal range. The cornea, pupil, and iris are normal unlike that found in many patients with ectopia lentis et pupillae (225200).
